翻訳と辞書 Words near each other ・ Rechtop in de wind ・ Rechts der Isar Hospital ・ Reception Tower Utlandshörn ・ Reception Yard railway station ・ Receptionism ・ Receptionist ・ Receptive aphasia ・ Receptive field ・ Receptive Services Association of America ・ Receptivity ・ Receptor ・ Receptor (biochemistry) ・ Receptor activated solely by a synthetic ligand ・ Receptor activity-modifying protein ・ Receptor antagonist ・ Receptor editing ・ Receptor modulator ・ Receptor potential ・ Receptor protein serine/threonine kinase ・ Receptor theory ・ Receptor tyrosine kinase ・ Receptor tyrosine kinase-like orphan receptor ・ Receptor tyrosine phosphatase ・ Receptor-mediated endocytosis ・ Receptorome ・ Receptor–ligand kinetics ・ Recess ・ Recess (album) ・ Recess (break) ・ Recess (Holy Roman Empire) Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Receptor editing ： ウィキペディア英語版 Receptor editing Receptor editing is a process that occurs during the maturation of B cells, which are part of the adaptive immune system. This process forms part of central tolerance to attempt to change the specificity of the antigen receptor of self reactive immature B-cells, in order to rescue them from programmed cell death, called apoptosis. It is thought that 20-50% of all peripheral naive B cells have undergone receptor editing making it the most common method of removing self reactive B cells. During maturation in the bone marrow, B cells are tested for interaction with self antigens, which is called negative selection. If the maturing B cells strongly interact with these self antigens, they undergo death by apoptosis. Negative selection is important to avoid the production of B cells that could cause autoimmune diseases. They can avoid apoptosis by modifying the sequence of light chain V and J genes (components of the antigen receptor) so that it has a different specificity and may not recognize self antigens anymore. This process of changing the specificity of the immature B cell receptor is called receptor editing. == References == 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Receptor editing」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.